Technical issues, the cutoff levels used to classify a gene as amplified or deleted and different quality assurance guidelines could also explain these discrepancies [ 21, 22].
On Friday, Syrian officials blamed technical problems for the cutoff.
This profile across age groups remained unchanged in more stringent analyses with higher cutoff values (Technical Appendix Figure 2) in which, despite levels of seropositivity decreasing with higher cutoff titers, the reduction was consistent across all age groups.
Laboratories providing ANA detection by HEp-2 cell assays frequently report different titers since cutoffs depend on technical equipment, expert knowledge, and patient population of the corresponding laboratory.
In order to remove the uncomfortable noise above 7 KHz, the reconstructed HF components are filtered with a low-pass filter, whose technical specifications can be summarized as (a) passband cutoff frequency, 3 KHz; (b) stopband cutoff frequency, 3.4 KHz; (c) maximum passband ripple, 0.8 dB; (d) minimum stopband attenuation, 80 dB.
We noted that the 10−6 ChIP-seq data failed to identify many ChIP-chip genes (45%), a result that likely reflects not only the more stringent cutoff threshold, but also several technical differences between the methods.
These discrepancies in the prognostic role of EGFR-1 may be related to different technical methods used, different antibodies tested, different cutoff values considered, major differences in the rate of EGFR-1-positive cases ranging between 13 and 82%.
Pro-government news portals quoted the minister of electricity as saying that the cutoff had to do with a technical fault in the valves supplying fuel to the power grid.
Other resolutions call on the Organization of African Unity and the nonaligned movement to suspend Egyptian membership, condemn U.S. Middle East policy, seek cutoff of any economic, financial or technical aid to egypt, ban Arab purchase of Egyptian securities, boycott firms doing business with Egypt, and appeal to the United Nations to move its regional offices out of Egypt.
Due to the variation in noise and specificity level between expression detection systems, each system must individually define its own threshold level cutoff for resultant confidence in signals above technical noise.
