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By materializing similarity data, knowledge propagation in Biozon becomes immediate, thus facilitating the task of function assignment.
This makes the task of function annotation transfer more complex (see Koonin, 2005, Annu. Rev. Genet., 39, 309 338).
Since module finding in biological networks is often motivated by the task of function prediction, we also perform a comprehensive evaluation in this scenario.
We took this approach because it is fast, an approximate and primary way to tackle a daunting task of function prediction of a large number of proteins.
For the specific task of function prediction in S.cerevisiae, we demonstrate that, surprisingly, a simple non-clustering guilt-by-association approach outperforms widely used clustering-based approaches that annotate a protein with the overrepresented biological process and cellular component terms in its cluster; this is true over the range of clustering algorithms considered.
These results are consistent with earlier work showing that a 'neighborhood majority' approach based on total counts performs as well or better than several sophisticated global network approaches (Nabieva et al., 2005), as well as earlier work suggesting that Neighborhood performs better than Mcode for the task of function prediction (Sharan et al., 2007).
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Martin's Minotaur, $24.95) by conflating the plots of a police procedural and an international thriller and giving her series sleuths the awkward task of functioning in two different worlds at the same time.
The supratidal foraminiferal taxa can act as an ecological indicator: through their observation it is possible to verify whether an artificial salt marsh accomplishes its task of functioning as an ecological unit with the community of organisms.
The task of Reduce function is to calculate the new clustering center in accordance with the intermediate results of Map function, and is for next round of MapReduce Job.
This is the task of the function (computeCommunitiesLeader, line 7 in Algorithm 2. Let (mathcal {C}) be the set of identified communities.
The psychomotor vigilance task and the GO/NOGO task, both of which are directly related to sustained attention, and the Paced Visual Serial Addition Task, which comprises a task of executive function, were administered during dim light, dark adaptation and light exposure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com