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Two cohorts of monkeys chronically exposed to lead during the first year after birth and their controls were tested during adulthood for choice accuracy on a learning and memory task, delayed spatial alternation (DSA).
PFC cognitive function was measured by the spatial working memory task delayed alternation.
Finally, after the presentation of an interference task, delayed recall was included (seventh trial).
In healthy participants, intranasal insulin administration over the course of 8 weeks improved performance on a declarative memory task (delayed recall) based on a word list that had to be remembered acutely and 1 week later [ 16].
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One hour after ingesting the capsule on each session, participants completed mood questionnaires and five impulsivity tasks: go/no-go task, delay discounting task, time estimation task, stop task, and the balloon analogue risk task (BART).
"Speed of memory" factor is derived by combining the reaction times of the four memory tasks (delayed picture and word recognition, numeric working memory, and spatial memory).
These tasks included a fixed consecutive number schedule (ability to complete an action to receive a reinforcer), a multiple fixed-interval/extinction schedule of reinforcement (high level of responding), and a delayed reward task (delay discounting).
Prior work by Lemmon et al. (2007) used simulations to demonstrate that self-triggered control systems can be remarkably robust to task delay.
Medial visual processing areas showed task-selective increases in activity during drug in both groups, while lateral regions showed decreased activity in young and increased activity in older participants at longer task delays.
Briefly, the analysis described below was performed separately for each of the working memory variables for each task (Delayed-match-to-sample, span, and spatial working memory) using Matlab (v. 2008a; http://www.mathworks.com/products/).com/products/
In neither of the two conditions were new letters presented during the task delay phase.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com