Five trials investigated changes in TA activity, with only one reporting an association between changes in TA function and associated changes in pain or activity limitation.
Validation of the proposed TA function of the Duf-linked proteins is required to establish them as members of the MazEF family.
It seems that the N-terminal coding region of the Pi-ta gene has played a critical role in the evolution of the Pi-ta function, similar to the role found in LRR.
A recent genome-wide screen for toxins has confirmed the TA function of the HEPN-MNT module, but contrary to the original prediction, identified the HEPN domain as the toxin in this system [ 43].
These ta-siRNAs function similarly to miRNAs by targeting complementary genes and initiating their degradation or translation arrest [3,4].
Over-expression of Ta-PHR1-A1 did not obviously alter the expression levels of Ta-IPS1.2, Ta-PHF1, Ta-PHO2, TaSPX3, Ta-PAP16, Ta-SQD2 and Ta-MGD2 (Supplementary Data Fig. S3), suggesting that transcriptional factors other than Ta-PHR1-A1 may function in Pi signalling in wheat.
This test structure, which is designed to mimic barrier performance at the bottom of vias where step coverage is a challenge, was used to determine the diffusion barrier properties of PVD deposited tantalum as a function of Ta thickness in 0.25-μm vias.
Like miRNAs, ta-siRNAs also function by targeting mRNAs via non-perfect sequence complementarity and induce target cleavage at the middle of ta-siRNA binding sites [7].
Examine the retention of any changes in MG, LG, SOL and TA neuromuscular properties, muscle fascicle function and functional mobility due to FAST in young adults with spastic-type CP 12 weeks following cessation of the FAST programme.
However, it is not known whether the TA modulates protein function.
