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Preference weights (utilities) for the SF-6D health status measure were derived using the recommended tariffs derived from a UK general population survey.
Unit costs for treatment-related physician visits and outpatient diagnostic procedures were based on official tariffs derived from the German physician fee scale called EBM (Einheitlicher Bewertungsmaßstab) [ 62] using a point value of €0.035048 [ 63].
The EQ-5D is a descriptive instrument that describes the health status of a patient and can be used to obtain an indirect estimate of utility by employing utility tariffs derived from a large scale lay population sample using the TTO method (Dolan et al, 1997) [ 11].
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First, given the expected usage under a given tariff (derived from the calibrated consumer's surplus function) is compared to the reported average usage under each given tariff.
We converted all EQ-5D scores to "utilities" through a tariff derived from a representative UK population sample.
31 Drug tariffs were derived from a Spanish drug cost database.
To calculate the EQ-5D utility score the application of tariffs previously derived from population based surveys investigating preferences for all possible health state combinations is undertaken.
These tariffs are derived from a valuation process in which members of the general population rank between 0 (representing death) and 1 (representing full health), the different health states described by the instrument.
For the purposes of this study, we applied the York A1 (Dolan) tariff set derived from a survey of the UK general population (n = 3337), which used the time trade-off valuation method to estimate utility scores for a subset of 45 EQ-5D health states, with the remainder of the EQ-5D health states subsequently valued through the estimation of a multivariate model [ 27].
These tariffs can be derived from two sources: 1) individuals who actually are in the health state (experience-based valuation), and 2) a general population sample (hypothetical-based valuation).
The York A1 tariff set was derived from a survey of the UK general population (n = 3337) which used the time trade-off valuation method to estimate utility scores for a subset of 45 EQ-5D health states, with the remainder of the EQ-5D health states subsequently valued through the estimation of a multivariate model [ 17].
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