Sentence examples for targets to validate from inspiring English sources
These two TFs were our targets to validate the method we developed to measure the activity of TFs in cells.
These results indicate limitations in current theoretical prediction methods and suggest that a realistic RNAi effort still requires testing multiple siRNA targets to validate those that are effective.
(D ) ChIP-qPCR analysis of Zfp335 binding at selected targets to validate ChIP-seq-based assessment of differential binding in blt / blt thymocytes.
The authors have selected different targets to validate different aspects of the method (CD45, FN1 and Dscam1) but their major figure describing SeqZip method highlights the strong bias to underrepresent mRNA isoforms that require multiple ligation events.
By studying a panel of these targets to validate the results, we found that estradiol stimulation triggered the association of c-Myb with promoters and that association correlated with increased target gene expression.
In the current study, we used the adenosine A3 receptor (A3R) as a sample target to validate the suitability of the used system and the experimental approaches.
The SOS response presents several properties that make it a suitable target to validate this type of analysis.
Finally, to prioritize the targets and to validate our metastasis-related genes in cell lines, a series of lung adenocarcinoma cell lines, including CL1-0, CL1-5, CL1-5-F4degrees-F4, with increasing degrees of invasiveness [23], was also subjected to microarray profiling.
One compound TALA with the highest affinity was isolated for further in vitro pharmacodynamic validation and target identification to validate the screen results.
These findings underline the potential importance of furin and other PCs for tumor targeting, but to validate RMS-P3/RR as tumor specific therapeutic target several points will have to be addressed.
Furthermore, we provide experimental results for a variety of benchmarks which intensively exercise the main components (CPU, Memory, HDDs, and NICs) of the target platforms to validate the accuracy of the equipment in terms of power dissipation and energy consumption.
