Sentence examples for targets to modify from inspiring English sources

Delivery of this dose of A53T α-syn via this particular AAV1/2 is thus a model to study endogenous compensation and could prove promising in discovering targets to modify disease course.

Their work established PITPs as pharmacological targets to modify PIP signaling in eukaryotic cells.

Although our knowledge is still primitive, the results obtained to date raise the possibility of using deiodinases as therapeutic targets to modify TH action in selected tissues.

This degradation process, with characteristic features of neovessel formation, neoinnervation and synovitis, provides us with potential targets to modify the degradation process in a positive way.

Since plant protein kinases and RLKs act as critical regulators of many signaling pathways, they represent important targets to modify pathways of interest.

As the genetic and molecular aberration of cancers and cancer subtypes are being elucidated, specific cellular pathways and associated molecular receptors are recognized as potential pharmacological targets to modify or arrest cancer growth.

This suggests that TNF is not the optimum target to modify entheseal disease.

A gene of interest is targeted to modify its function, and an enzyme cuts that gene's DNA sequence, breaking the structure of the DNA.

Aiming to promote their functioning in CBC, efforts targeted to modify the crop environment are focusing on the determination of their non-crop host plants that can support the predators' persistence as well as the emigration of these predators to the nearby crops.

These results indicate that GFAP is a major target to modify astroglial reactivity and consequently neuron-glia interactions for therapeutic purposes.

The specific RelA acetylation on Lys310 represents a molecular target to modify gene transcription and neuronal resilience to ischemic injury.