Sentence examples for targets cluster from inspiring English sources

The majority of pharmaceutically relevant drug targets cluster into densely populated target families, thus offering a novel approach that complements the currently favoured screening paradigm in medicinal chemistry.

Previously identified potential drug targets cluster near the top of our prioritized list, lending credibility to our methodology.

The remaining clusters show a high variance (cluster 3; mean LOD = 0.21, variance = 0.02) and a common depletion of microRNA targets (cluster 1; mean LOD = −0.36, variance = 0.07).

For example, imatinib targets the Philadelphia chromosome-positive (Ph+) leukemia [ 13], and the anti-human antibody preparation rituximab targets cluster of differentiation (CD) 20 that is only expressed in B cells [ 14].

Most targets cluster in the region for RMS of y −  x below 15 and slope below 1.3, representing similar domain-based evaluation and whole-chain evaluations (black and blue points).

This multi-grain data parallel approach targets clusters built from commercially available SMTs and multicore processors.

The genes of SP1 (Spl), E2F1 (E2fl) and FOXO1 (Foxo1) all belong to time profile 7 with a common up-regulation throughout the injury response, but have different targets clusters.

More surprisingly, the deletion of RPN4 slightly but reproducibly decreased the selenite induction of several Yap1p targets (clusters 1 and 4).

Those concerns include a contention that putting the center in Walt Whitman Park would create a "terror target cluster" because of its proximity to targets like the Brooklyn Bridge, subway stations and a federal courthouse that was the site of a bombing in the 1980's.

Then, genes belonging to the target cluster (shown in Figure 5) are upregulated (b).

The b-value of the background seismicity was calculated using hypocenters other than the target cluster within a range of ± 0.4° from the mainshock's epicenter of the target cluster.