Sentence examples for targets can be generated from inspiring English sources

Design alternatives for products and processes matching a priori defined targets can be generated and verified through the PPD-lab.

We have shown that highly stable binding proteins for a wide spectrum of targets can be generated through mutagenesis of the Sso7d protein from the hyperthermophilic archaeon Sulfolobus solfataricus.

With the virtual PPD-lab, users can test their design ideas on model-based computer-aided tools before performing experiments to validate the designed product; also, manifold product and process alternatives matching a priori defined targets can be generated.

And specific varieties of antibody, aimed at specific targets, can be generated from cultures of genetically identical cells created for the task in other words, cellular clones.Ipilimumab locks onto and thus blocks the action of a protein, CTLA-4, which sits on the outer membranes of immune-system cells called T-lymphocytes.

Finally, a logical framework for the development of therapeutic targets can be generated through in silico-based reverse engineering of transcriptome data – this has previously been used to identify signaling pathways e.g., CREB targets [ 10] as well as master regulators – cardinal, potentially targetable genes that regulate nodes in pathways [ 32, 33].

New leads for a therapeutic target can be generated through (1) known inhibitors for the target or a much related target, (2) high-throughput screening (HTS) of corporate compound collections, or (3) the screening of natural product libraries.

Based on the results of the in vitro experiments the hypothesis of a specific binding to the target can be generated.

Repertoires of antibodies against a specific candidate target can be generated by a variety of methods.

For the LMH code, as the same prediction target can be generated by different input configurations, and there are two LMH outputs, we compute the predictions for all input combinations containing the particular tissue and average them into a single prediction for testing.

In this case, a default configuration respecting either the target throughput or the BER objective can be generated.

Using this kind of analysis, hypotheses about on-target as well as off-target effects can be generated, that reflect the drug action in the population and under everyday life conditions.