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Here, we provide evidence that meprinβ targets and processes E-cadherin thus affecting intercellular adhesion.
These results suggest that DHA and lysine exert their beneficial effects by modulating distinct cellular targets and processes.
The 4T1 syngeneic metastatic breast cancer model may be useful to validate potential gene targets and processes implicated in cell migration and intravasation.
Upon further testing and refinements, which will require additional data and information, the model will have the potential of assessing the effects of drug interventions on targets and processes located downstream of the DARPP-32 system.
Conservation of co-expression is a powerful approach to identify gene targets and processes with potential similarity and divergence between mice and humans, which has implications for drug testing and other studies employing the mouse as a model organism.
The relation between Cat X levels and response to therapy has not been reported, however, anticancer drugs may interfere with Cat X targets and processes, also regulating its expression and secretion.
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"I'm not saying all these platforms will stay the same forever," he said, "but in the near-term they will remain and gain technologies to acquire targets and process information and disseminate that information much more quickly".
This image was targeted and processed in one E.M.D.R. session.
Differential activation suggests both target and process-specific regulation (Sapetschnig et al., 2002).
Even at the current limited level of understanding of target biology and processes to intervene, many targeting paradigms are incredibly simplistic.
In the case of progranulin, the potential effects of miR-29b knockdown on other mRNA targets and biological processes must be considered.
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