"Every ten years we go through a rethink of targeted versus one voice," says McGhee Williams Osse, co-chief executive of Burrell, a Chicago-based agency specialising in the African-American market.
Randomised comparisons of targeted versus routine treatment are lacking.
The study compared two different types of multidimensional assessment (targeted versus universal) and two different management models (primary care team versus multidisciplinary geriatric evaluation team).
Among the randomised trials comparing targeted versus routine approaches, three out of four employed state targets, 26 28 29 an approach that has been favoured as being more appropriate than assessing changes from baseline.
In contrast, the breast cancer cell line SKBR-3 highly expresses HER2 but is negative for CEA, which provided the possibility of evaluating targeted versus untargeted iNKT cell-mediated cytotoxicity.
We anticipate that more work using ex vivo tissue sampled in a targeted manner will in particular have some utility in exploring the distribution of Gleason patterns when we target versus times when we do not.
Nevertheless, in trials where the T2 were incorrectly reported L-FFA showed a significant increase in activity (Z = 2.56, P < 0.05) for fearful T2, targets versus neutral T2 (Fearful-T2_Incorrect-T2 vs. Neutral-T2_Incorrect-T2).
