Sentence examples for targeting unit from inspiring English sources
Glycyrrhetinic acid (GA) was used as a targeting unit to ensure specific delivery.
This behavior suggests that the gH625 is capable of targeting brain tumor with the same efficiency of the more often adopted FA targeting unit.
This work demonstrates the preparation of amphiphilic block copolymers with remarkable reproducibility of each block and the dual functionalization of the chain ends with a targeting unit and a fluorescent moiety.
The fluorescent nano-conjugates were composed of poly 2-vinyl-4,4-dimethyl azlactone (PVDMA) as the linker, folic acid as the targeting unit and amino-Rhodamine B as the fluorescent ligand.
By contrast, when P2VP blocks and the targeting unit were buried by the PEO shell at physiological pH, micelle stealth properties were improved, allowing their future systemic injection with an expected long circulation in blood.
Upon protonation under acidic conditions, pH-sensitive poly 2-vinylpyridine) (poly 2-vinylpyridineretched, exhibiting P2VPtive charges at the periphery of the micelles as well as blocksa model targeting unit.
NPs were prepared from PLGA-PEG-NH2 copolymers and the coupling of anti-EGFR mAb (as an antibody for pancreatic cell for targeting units) to glutaraldehyde-activated NPs at the surface was studied.
Amine groups were chosen to couple targeting units by using two different conjugation techniques, one involving glutaraldehyde as a cross-linker and other method involved MBS modification of NPs.
The advantages of such particles are their small size, the solubilization of hydrophobic drugs, and the possibility to functionalize their surface with targeting units.
Where necessary, the metal binding domains and biological targeting units were deprotected using standard procedures prior to testing (see ESI † for full details).
Testing of sensors bearing representative targeting units in pancreatic islet cells demonstrated not only their differential localisation but also their divergent responses to extracellular stimuli, suggestive of applications in the study of Zn2+ trafficking in the subcellular space.
