Even without targeting surface ligands, superparamagnetic iron oxide NP [SPIOs] diameters greatly affect in vivo biodistribution.
This study demonstrated the feasibility of targeting surface decorated NPs to multidrug resistant gliomas.
On the basis of these anti-CD133 CSC therapies, CART cells targeting surface marker CD133 can probably effectively eliminate CSCs.
Attempts are underway to develop antibody-based vaccines against the organisms by targeting surface virulence factors, including MSCRAMMs [17].
CPMV was labeled with cyanine dye sulfo-Cy5 using NHS-activated esters targeting surface lysines.
This cleavage event exposes a reactive thioester that allows covalent attachment of C3b to target surfaces.
The shape of particles also impacted their adhesion on targeted surfaces.
Parallel SEM mapping of both film and target surfaces pointed to a correlation between changes in film composition, droplet density and target surface deterioration.
These chimeric receptors, called T bodies, target surface antigens in an MHC-independent manner [72].
As shown here, ASSET also targets surface residues in 3FTXs, PLA2 enzymes, serine proteases and metalloproteases.
