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Finally, we highlight successful applications of rational design principles to provide chemical probes and lead compounds targeting structured RNAs.
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Broken links between retinal ganglion cells and target structures throughout the brain spell permanent vision loss.
This observation predicts reduced output of MSSNs to target structures along the direct and indirect pathways.
The primary role of the afore mentioned proteins is adherence to target structures.
Table 1 summarizes the distribution of unpaired bases within the siRNA targeted structures.
Thus, it is reasonable for any generated idealized structure P i to be considered similar to target structure P0.
They are highly targeted structures.
How is my target protein structured in these samples?
After 4 7 d of recovery, probes were lowered towards their target structures.
Nevertheless, there are still limitations and one of them is the size of the target structure.
Finally, we asked whether this mechanism might be generalizable to other types of target structures.
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