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It is important to note that we have developed the framework to address the needs for a more general purpose, targeting scenario engineering as an extension in future.
It is important to note that we have developed the framework to address the needs for a more general purpose, targeting scenario engineering.
The most cost-effective targeting scenario is shown in Fig. 6c, where PrEP is targeted to 25 35-year-old women when there is a baseline incidence of 0.8% per year at 25 35-year-old
More recently, a similar targeting scenario was discovered for the mitochondrial Flap endonuclease 1 (FEN1, or FENMIT to the authors) or the oligoribonuclease REXO2 where a 'cryptic' targeting signal from alternative translation initiation generates a truncated isoform of this protein that permits import [33,34].
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In this paper, we are targeting scenarios where energy harvesting (based, for example, on solar panels) is the only power source at the BSs.
Maps of these two benefits are used to develop improved spatial targeting scenarios that deliver significant efficiency gains in comparison to the existing scheme design.
Since there are no current targets for adult obesity at the national level or for the West Bank, and since obesity is increasing and is predicted to continue to increase, we used a Mediterranean country, Turkey targets (scenario 1), WHO targets (scenario 4) and WHO regional targets (scenario 5).
Table 4 lists CFR results using the aggressive pharmacodynamic exposure targets (scenario 1) for each prescribed antimicrobial regimen against each of the outpatient respiratory bacteria.
Table 5 lists CFR results using the conservative pharmacodynamic exposure targets (scenario 2) for each prescribed antimicrobial regimen against each of the outpatient respiratory bacteria.
A similar reduction in absolute socioeconomic inequality comparing the least to the most disadvantaged children is seen for the progressive universal Scenario 2 and the proequity targeted Scenario 4 (15.7%).
Finally, an extension to multi-target scenarios will also be considered.
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