Sentence examples for targeting resulting in from inspiring English sources

Several studies have indicated that loss of glycosylation can lead to improper folding and targeting, resulting in decreased function and compromised structure [36] [37].

Accordingly, the GluRδ2 ectopically expressed in Golgi cells responds to the signals that mediate such precise targeting, resulting in polarized localization not only in the ascending and descending tracts but also in the proximal-distal dimension of the ascending tract.

The C829T variant interferes with miR-24 targeting, resulting in DHFR overexpression and MTX resistance [ 73].

A number of papers have described successful triplex targeting, resulting in a reduction in Ets factor binding at the adjacent EBS (for review see [ 4]).

Therefore in U87 cells pLG72 might enhance oxidative stress via the interaction of DAAO and blockage of the DAAO peroxisome targeting, resulting in producing H2O2 in cytosol and/or mitochondria.

Moreover, biodistribution studies revealed high and selective tumour targeting, resulting in tumour to blood ratios ranging from 6.0 at 24 h to 45.9 at 72 h p.i.. Normal tissue accumulation of I-L19-SIP was significantly lower than previously reported for Br-L19-SIP.

EGFR and MET targeting had little effect on cell viability, whereas AXL targeting resulted in ∼50% reduction of mesothelioma viability.

In addition, the bottom row shows that better targeting resulted in less erroneous intensity variations within the myocardial wall.

Knockout of src and tks5 through CRISPR/ Cas9 targeting resulted in a reduction of primordium size and loss of migration.

Specific CD4 targeting resulted in augmented skin hyperplasia and dermal inflammation in TPA-treated WT mice, but had no effect on EPI−/− skin.

The lack of the CD25 sink and improved tumor targeting resulted in increased systemic exposure of IgG-IL2v compared with IgG-IL2wt in immunocompetent C57BL/6 mice.