Sentence examples for targeting pathways from inspiring English sources

This suggests that drugs are effective if they could successfully repress the ectopic activity of their targeting pathways.

In these applications, bringing the micelles to the desired site is essential for therapeutic success, which can be accomplished by exploiting either active or passive targeting pathways.

This dependence is driven by the activation of MYC and HIF1-α [109] and consequently, targeting pathways regulating glucose/glutamine metabolism may be of relevance for cancer treatment.

Our results identified RBP-J as a key regulator of M2 polarization and suggest that targeting pathways that modulate RBP-J activities has the potential of altering macrophage polarization processes and subsequent immune effector responses.

In contrast to histological studies, radionuclide imaging has the advantage of offering non-invasive, prospective longitudinal assessment of angiogenesis, of the whole tumour and metastases, by targeting pathways involved in the process [3].

Our results suggest that hSnd2, Sec62, and SRP and TRC receptor each provide alternative targeting pathways for short secretory proteins and define rules of engagement for the actions of Sec63 and BiP during their membrane translocation.

These results indicate that PTS1 specifically target lycopene pathway enzymes into peroxisomes and this targeting pathway was strong enough to overcome their inherent targeting program.

The identification of a new targeting pathway could pose as an important target for an antimicrobial agent, especially in light of a potentially differing targeting pathway from eukaryotes.

The Tat (twin-arginine translocation) system is a protein targeting pathway utilized by prokaryotes and chloroplasts.

Instead, co-targeting pathways downstream of mutant KRAS has emerged in pre-clinical studies as a promising therapeutic strategy.

A: Whole blood miRNAs target pathways.