Sentence examples for targeting of compounds from inspiring English sources

In developing new antioxidants it will be useful to utilize endogenous processes to activate and recycle the molecules in parallel with the targeting of compounds to cells and organelles in ways that are not limited by the constraints that impair the distribution of endogenous antioxidants.

Among the current trends in the development of biopesticides is the control of release rate and targeting of compounds by nanoencapsulation, as this technique can increase the stability and solubility of natural products and, consequently, increase their efficacy.

For example, Badruddoza et al. in 2013 synthesized uniform nanocomposite for cell targeting of hydrophobic compounds.

The known targets of compounds in FFDS were collected from STITCH62 (http://stitch.embl.de/, version 5.0) with a higher interaction score (confidence >= 0.7).

Computational chemogenomic (canSAR) analysis of prostate cancer mutations identified 11 targets of approved drugs, 7 targets of investigational drugs, and 62 targets of compounds that may be active and should be considered candidates for future clinical trials.

Cell-based assays based on disease-specific phenotypes, such as cell proliferation, migration, and invasion in the case of cancers, have been used to identify lead compounds1, 2. However, elucidation of the MoA and molecular targets of compounds obtained by phenotypic screening remains challenging, and is therefore a rate-limiting step for drug discovery using cell-based assays.

This may be useful for suggesting potential additional targets of compounds for which it is still unclear.

Reduction of beta-amyloid levels is a common target of compounds (such as apomorphine) under investigation.

Finally, we used CRISPR/ Cas9-targeted mutagenesis in zebrafish to genetically validate predicted targets of compounds.

Next, the lists of known targets for the three compounds were computationally expanded to 'possible targets' defined as targets of compounds similar to RSV, FF and T09.

BLASTP with default parameters was performed against the list of targets of compounds found within DrugBank to align the potential drug targets from E. coli O157 H7.