Sentence examples for targeting module from inspiring English sources

We designed oligonucleotide nanostructures to facilitate assembly of a cell-internalizing aptamer (targeting module) with a large functional RNA (payload module) and to enable modular, targeted delivery by using appropriate aptamers to direct cell specificity of the RNA payload.

Therefore, it is unclear whether the BD serves as a targeting module for BRD9.

As a targeting module, aptamers allow for improved delivery of drugs to tumour cells while minimizing the side effects often associated with the drugs.

Thus, CaMKIIbeta functions as a targeting module that localizes a much larger number of CaMKIIalpha isozymes to synaptic and cytoskeletal sites of action.

Furthermore, the average BRD9 read density at all of its targets progressively decreased over time with I-BRD9 treatment (Fig. 6f, g), in support of the BD functioning as a targeting module for BRD9.

Importantly, when the targeting module was omitted and cells were treated with 3WJdB+DFHBI-1T only, MFIs were equivalent to those observed for DFHBI-1T-stained cells, indicating little or no cell binding by functional 3WJdB alone.

Together, these studies demonstrate that reader domains in BAF complexes can serve as targeting modules for BAF complex recruitment.

However, these endogenous bio-ligands can themselves serve as targeting modules either in their native form or engineered as carrier cargo.

The normal function of PKC is under the coordinated regulation of five major mechanisms illustrated: phosphorylation, dephosphorylation, membrane targeting modules, degradation, and anchor proteins.

We cloned the promoter of urg1 (uracil-regulatable gene) to create several PCR-based gene targeting modules for replacing native promoters with the urg1 promoter (Purg1) in the normal chromosomal locations of genes of interest.

Cancer imaging requires small, fast penetrating but tightly binding targeting modules, with a rapid plasma clearance.