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18F-FDHT targeting is based on an overexpression of the androgen receptor.
In particular, this new strategy for NPs-brain targeting is based on the surface engineering of NPs, using a glycopeptides (g7)–derived PLGA [3], [5], [6].
Active targeting is based on the overexpression or exclusive expression of different receptors or epitopes on tumor cells [ 4].
Passive targeting is based on the so-called enhanced permeability and retention (EPR) effect (Matsumura and Maeda, 1986; Maeda et al, 2000).
In countries or centers where chemotherapy is less widely prescribed or where targeting is based on other tests, there may be a reduced benefit and justification of the test cost [ 26].
Metabolic targeting is based on the assumption that cancer cells show increased activities of several metabolic processes (for review see Jager et al. [ 11]), and indeed, malignant transformation of cells has been found to be associated with increased metabolic activity [ 12].
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Segmentation and targeting are based on factors such as audience interest profiles, demographics, social influence and realtime conversations.
Targeting was based on new, separate CT scans for each split course.
The 80% target is based on the fact that fibre loss in recycled paper manufacture requires an annual input of around 20% virgin fibre to be sustainable.
The chancellor's 2011/12 PSNBR target is based on the economy growing by 1.7% in 2011 and by 2.5% in 2012.
This target is based on World Health Organisation's "Five Moments for Hand Hygiene", a guide to the best hand-washing practices for different types of contact with patients.
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