Sentence examples for targeting integration of from inspiring English sources

Briefly, ViDOS was a cluster, randomized controlled trial in 40 LTC homes (21 control; 19 intervention) that examined the feasibility and effectiveness of a knowledge translation intervention targeting integration of best practices for osteoporosis and fracture prevention.

Two relevant observations stand out: first, the need for user-friendly tools targeting integration of heterogeneous datasets; and secondly the relevance of translational medicine, as shown by the interest of incorporating clinical data in most integrative omic studies.

These results demonstrate that FnCas9 can mediate targeted integration of synthetic DNA donors via in vivo directional ligation as an alternative to integration by homology-directed repair mechanism; however, further improvement in the donor genome junction fidelity is needed.

Next, by injecting Cas9-gRNA Asipa with ssODN:AsipA into F344 embryos, we attempted targeted integration of a 19-bp nuCas9-gRNA Asipant at the Asipa locus to recover the non-agouti phenotype (Fig. 3a).

In this study, a plasmid was designed to target integration of a gfp-bsd gene into the Babesia bovis ef-1α locus.

Availability of the transient transfection system was critical for the further development of a stable transfection technique using a plasmid designed to target integration of a gfp-bsd gene into the B. bovis ef-1α locus.

Moreover, we demonstrate that these MSTN TALENs can facilitate targeted integration of a mCherry expression cassette or a larger muscular dystrophy gene (dysferlin) expression cassette into the MSTN locus in mouse or human cells.

Meanwhile, the Mosdi1 R left flank and right flank, which will facilitate targeted integration of foreign DNA into wild type Mosdi1 locus, was introduced in the vector.

These plasmids allow targeted integration of the fluorescent marker into the sdi1 locus, thereby conferring resistance against the fungicide carboxin.

The PITT technique enables targeted integration of a single-copy transgene into a predetermined locus by Cre-loxP-mediated recombination and guarantees a stable and reproducible transgene expression.

We used the identified sdi1 sequence to construct a vector, pCeGFP, which allows targeted integration of DNA into the genomic locus of the succinate dehydrogenase subunit-encoding gene.