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Collaborations between funders and with other stakeholders were considered helpful for supporting broader, long-term evaluations and strategically targeting impact evaluations.
Detailed data for all experimental validation studies are presented in Additional file 2. In summary, we identified osteo-inhibitory targets for miR-10a, miR-22, miR-26a, miR-26b, and miR-29b with the highest targeting impact resulting from miR-26a, miR-26b, and miR-29b expression.
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This implies that ZnO NPs may have targeted impact on coelomocytes as a result of preferential accumulation and subsequent in situ molecular damages by liberated Zn+ ions [2] at higher concentration.
Aim: The main reason to use the nanoparticles is to make active substrate not to decay at the injection site, to target impact zones, to provide continuous active substrate oscillation and to improve the bioeffect of administration of drug.
For these clients, Morgan Stanley is weighing a customized approach to matching investments and values, likely carving out small parts of a portfolio for targeted impact investing, and is evaluating donor-advised funds as a logical place for impact investments that offer a concessionary return.
Madrid and Manchester have this type of integrated climate change plan, whereas London, Copenhagen, and Rotterdam have already created stand-alone adaptation strategies that exclusively target impacts of climate change.
No study targeting the impact of silicone breast implants on body composition measured by bioimpedance analysis was identified.
There is need for production and dissemination of key health messages of CS targeting high impact interventions.
ASPIRE ultimately aims to develop and undertake a randomised evaluation of the effects of implementation packages targeting high impact recommendations.
By degrading dietary substrates, the gut microbiota produces several metabolites that bind human pharmacological targets, impact subsequent signalling networks and in fine modulate host's metabolism.
b Photograph of soft-point hunting bullets depicting the soft-point construct and incomplete hard-metal jacket; significant deformation of this bullet caused by target impact is also depicted.
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