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Since then, several small molecule inhibitors targeting HER signaling have been developed, such as the reversible HER1/HER2 inhibitor lapatinib and the irreversible pan-HER inhibitor neratinib [ 4, 5].
"FBI is not targeting her".
They were targeting her grandfather.
Now her assailant is targeting her minions.
Which wouldn't stop the Boss from targeting her.
Hunt's mother, Susan, has accused Saratoga Springs police of targeting her son because he was black.
Similar(14)
Another tumor marker, HER-2/neu, is an oncogene whose amplification or protein overexpression predicts response to a monoclonal antibody targeting HER-2/neu, as well as to anthracycline-based chemotherapy.
We determined specificity and sensitivity of AVEC in targeting HER-2 domains on the cultured cell lines by flow cytometry (FCM) and fluorescently activated cell sorting (FACS) (Fig. 2c e).
Trastuzumab is a monoclonal antibody targeting HER-2.
One alternative approach to targeting HER-2 is via small molecule HER-2 kinase inhibitors, currently developed in the clinic.
Several monoclonal antibodies targeting HER-3 are now being developed by major pharmaceutical companies and some of them entered clinical testing.
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