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EPC clones stably expressing rhabdoviral specific siRNA sequences could be a strategy to further investigate the use of RNA interference for targeting costly fish pathogenic viruses.
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Traditional policy levers such as taxing or prohibiting "bad" choices or subsidising or requiring "good" ones, can work, but they are hard to target and costly to enforce.
On the other hand, perhaps because of the ruckus caused by his withdrawal of child benefit from high earners, Mr Osborne shied away from further attacks on the principle of universalism in the welfare system: he might, for example, have targeted the costly perks dispensed to pensioners regardless of their wealth.
Conclusion: Providing physicians with simple pharmaceutical cost information and telephone reminders decreased the use of targeted more costly medications.
[ 48] Furthermore, examples in the medical literature suggest that the use of physician facilitators have favorable cost-benefit ratios when targeted at costly system issues.
Questions were raised about the proportionality of covert tactics and of such a lengthy and costly operation targeting green campaigners planning to invade Ratcliffe-on-Soar power station near Nottingham.
Better predictive models might allow appropriate targeting of cumbersome or costly preventative interventions and enhance the power of clinical studies examining such interventions.
Not only would this be costlier than targeting lone parents; by increasing benefits, it would make work less attractive.
There are three ways in which a universal program might generate sufficient additional benefits to make it a better investment than a less costly targeted program.
Effective solutions for counteracting these threats, however, require synthesis of high quality evidence, appropriately targeted activities, typically costly implementation, and rapid re-evaluation and adaptation.
It is important to develop methods that more accurately assess efficacy of cetuximab in patients with incurable SCCHN since this costly targeted agent benefits a minority of patients.
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