Sentence examples for targeting compounds from inspiring English sources

Whereas anti-angiogenic drugs aim on the inhibition of new vessel formation, vascular targeting compounds are designed to selectively destruct preexisting tumor blood vessels leading to secondary tumor cell death.

Nature products chemistry research has become much more applied, targeting compounds, which exhibit pharmacologically useful biological activities.

The microtubule targeting compounds engage at the mitotic spindle checkpoint where they block cell cycle progression at mitosis ultimately leading to apoptosis (Bhat and Setaluri [2007]).

Each of these sites can be used to attach other biologically active molecules to the dendrimer, such as the drug, cancer-specific antibodies, or similar targeting compounds.

In contrast to the well-known bone targeting compounds [18F]NaF and [177Lu/153Sm]EDTMP DOTA-bisphosphonates can be used as a therapy and imaging agents, when labelled with β- and positron emitting radio metals.

While bedaquiline is known to target ATP synthase [10,11] it was not shown to be similar in TB Mobile to the ATP synthase targeting compounds in the test set (Additional file 4: Figure S2-7).

The structures of the targeted compounds T-1 and T-2 for synthesis are shown in Fig. 2a.

13065_2012_432_MOESM1_ESM.doc Additional file 1: Synthetic route to target compounds 7a-7s.

Scheme 1 Synthetic route to target compounds 7a-7s.

Scheme 1 Synthetic pathway to target compounds 5a 5n.

This is important in estimating efficacy for liver-targeting compounds (e.g., statins), potential liver toxicity of nonliver-targeting compounds (e.g., endothelin receptor antagonists), or potential drug drug interactions in the liver.