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The most selective dual PARP DNA targeting agent 14b was found to possess dual DNA and PARP targeting properties.
MUC1 DNA aptamer with 5′-NH2 functional group was conjugated to the self-assembled conjugate as a targeting agent.
Before testing his theory, Kobayashi's team added a targeting agent to the fluorescent compound, to help it home in on cancer cells.
Radiolabeled J591 antibody has potential as a targeting agent for solid tumor vasculature and lesion detection.
The carbohydrate serves as a targeting agent and newly identified fragments increase its interaction with the lectin.
The 18F-labeled molecule was synthesized in 79% yield after HPLC purification to remove the unlabeled targeting agent.
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Within this study, BPAMD showed to be a potential bone-targeting agent to treat skeletal metastases with 177Lu.
Collagelin is a new collagen-targeting agent which may be useful for non-invasive detection of fibrosis in a broad spectrum of diseases.
As a cancer-targeting agent, poly epsilon-caprolactone) micropoly epsilon-caprolactoneed with a NIR dye and functionalized with an RGD (argenine-glycine-aspartic acid) peptide, were used.
Chemotherapy resistance acquired from the damaged TME but attenuated by a WNT16B-targeting agent.
The receptor tyrosine kinase AXL is thought to play a role in metastasis; however, the therapeutic efficacy of an AXL-targeting agent remains largely untested in metastatic disease.
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