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We evaluate the performance and the limits of photogrammetric methods by targeting a set of fundamental parameters necessary to study biogeomorphic feedbacks at each of the three nested spatial scales and, when possible, propose appropriate solutions.
An in vitro screen was performed using retrovirally encoded shRNAs targeting a set of 100 known, or putative, cancer-related genes.
A regression model was adopted to identify the significantly associated miRNAs targeting a set of candidate genes frequently involved in colorectal cancer MSI and CIN pathways.
Overall, our study revealed that a highly multiplexed universal custom SNP array "rice OPA-1" designed for Illumina GoldenGate assay targeting a set of stress-responsive genes was efficient enough to rapidly genotype rice accessions with high precision and success rate.
In their paper " Multiple regression analysis of mRNA-miRNA associations in colorectal cancer pathway," F. Wang et al. adopted a regression model to identify the significantly associated miRNAs targeting a set of candidate genes frequently involved in colorectal cancer (CRC) pathways.
This microRNA suppresses endothelial migration by targeting a set of genes in cancer cells that drive endothelial migration, by activating IGF1R, which is a promoter of endothelial migration, and inhibiting the endothelial MERTK receptor, which is a suppressor of endothelial migration [ 16].
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It is therefore possible that FMR4 may also target a set of genes in trans resulting in its antiapoptotic properties.
Thus, miRNAs that target the 3'UTR of a particular mRNA may also target a set of mRNAs with similar function.
They target a set of PPR genes including Glyma09g30500, Glyma16g27800, Glyma09g39260 and Glyma09g39250.
Our data also support the notion that a certain mRNA can be targeted by several miRNAs, and in particular an miRNA may target a set of mRNAs.
It has been reported that a siRNA, TAS4-siRNA81, targets a set of MYB TFs such as PAP1 and MYB113 in Arabidopsis [ 39].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com