Sentence examples for targeted variation from inspiring English sources

We analysed the number of reads that covered the variations in 24 genes frequently known to be related to inherited cardiomyopathy; we considered that a read depth ≥30 reads (30x, Q30 = 99.9% chance of the correct base being called) for each targeted variation indicated that it was correctly covered [ 20].

Single Nucleotide Polymorphisms (SNPs) can serve as an alternative type of genetic marker for analysis of degraded samples because the targeted variation is a single base.

For example, sensitivity analyses targeting variation in concentration response, including lag time in presentation of exposure-related health effects, long-term exposure effects, and hypothetical thresholds for PM concentration response, are performed.

Drug molecules designed along those principles are usually rigid and unable to adapt to target variations arising from naturally occurring genetic polymorphisms or drug-induced resistant mutations.

Because of the small numbers of miRNA members and target genes, target variations #5, #10, #11, #15, and #16 in Table 1 had no significant GO terms.

Coat color genetics in mink is the first interest targeted, as variation is common; the fur color, markings (if any), or the patterns separate the color types.

[7] Still, this corresponds roughly to leaving out a single target out of 14 in the NNRTI set (+/− 10% of target variation).

Finally, we investigated the extent of off-target variation and its effect on genotype calls.

Another advantage of the use of oligodeoxyribonucleotides as targets is that we can analyze the specificity of single nucleotide mismatches without effects of target variation, such as variations in target length due to random fragmentation [ 15, 16].

a The 'breast/up-regulated' miRNA cluster data from Volinia et al. (2006) using the target variation #6 (see Table 1) was used.

VINOs may represent off-target variation in the genome near the SNP queried by a probe set and show a consistent, low-intensity cluster during genotyping.