Sentence examples for targeted uptake from inspiring English sources
With targeted uptake of NPs, there is the potential to increase the dose to the tumour whilst maintaining or reducing dose to surrounding normal tissue.
Thus in the present study, we have demonstrated that PLL-coated BNNTs functionalized with the folate ligand enable targeted uptake of the nanotubes by tumor cells by receptor-mediated endocytosis.
Targeted uptake of therapeutic agent in the cell-, tissue- or disease-specific manner represents a potential technology for the treatment of HCC.
Therefore, anti-EGFR/HGNs can increase the targeted uptake of HGNs by HeLa cells and enhance radiocytotoxic targeting of cervical cancer at megavoltage radiation energies.
Even though the enhanced permeability and retention (EPR) effect of the tumor (due to the leaky vasculature and lack of lymphatic drainage in the tumor) or receptor-mediated targeted uptake of imaging agents may facilitate probe accumulation in the tumor over other tissues [ 35], the liver background for nonspecific probe accumulation can still be high.
In this experiment, the CF750-Dmab scFv -Fc antibody was CF750-Dmab scFv -Fc-Dmab(sCF750-Dmab scFv -Fc tumor tantibody, uptake, and clearance.
Furthermore, the core/shell nanogel delivery system employed here is readily amendable to selective surface functionalization by a variety of targeting molecules, offers a protective environment for sensitive cargo, and shows excellent targeting uptake and delivery in serum containing medium.
The aim was not simply to evaluate effectiveness, but also to assess whether schemes were delivering as expected and how their impact could be enhanced, for example by improving targeting, uptake and other aspects of implementation.
These particles were targeted for uptake via microfold cell (M-cell) in Peyer's patches of small intestine using M-cell targeting ligand, Aleuria aurantia lectin.
More importantly, we also provide specific insights into the effect of HSA adsorption on the in vivo transportation of nanoparticle (i.e., immune response and targeted cellular uptake).
GNC size is another factor related to targeted cellular uptake.
