As well as blocking efforts to introduce a target to decarbonise the UK's power sector by 2030, George Osborne is now understood to be pushing for slower ambition across the EU by opposing a new renewables target to replace the current one which will expire in 2020.
Homology-directed repair (HDR) is the general approach of using sequence homology for genomic targeting to replace an endogenous locus with foreign DNA and encompasses homologous recombination (HR -based as well as HR -basedndent mechasisms (see Box 1).
But it is quite true that the leave campaign and Ukip never committed to any new target to replace David Cameron's failed pledge to reduce net migration to the "tens of thousands".
The 17 goals were presented to the UNGA last year by an open working group of 70 countries that had been charged with producing a set of targets to replace the millennium development goals, which expire at the end of 2015.
The resulting 'Bali roadmap' is a global warming pact that starts a two-year process of negotiations designed to agree a new set of emissions targets to replace those in the Kyoto protocol.
Chelsea – whose long-term targets to replace Mourinho remain Pep Guardiola and Diego Simeone – and Vitesse Arnhem have been cleared by the Dutch football federation (KNVB) of having an 'improper relationship' after an independent investigation into links between the clubs.
Cashman's prediction of a slow off-season appeared much more realistic with Wednesday's news that two of the team's top targets to replace Rodriguez during his recovery from hip surgery had signed elsewhere.
Cardiff City have made Ole Gunnar Solskjaer their No1 target to replace Malky Mackay, with Vincent Tan, the club's owner, optimistic that he can convince the former Manchester United striker to leave Norway in favour of the chance to manage in the Premier League.
The interminable discussions continue about targets to replace the millennium development goals (MDGs) when they expire in 2015, but there is a gradual shift towards not just what the world should try to achieve, but how to go about it, known in the jargon as "means of implementation".
Starting this week and continuing over the next year or so, the UN's usual Who's Who of politicians and officials from governments and international agencies will meet to draw up a new list of targets to replace the Millennium Development Goals (MDGs), which were set in September 2000 and expire in 2015.
