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Design of experiments is targeted to generate informative data and to reduce the experimentation effort as much as possible.
The first stage was targeted to generate a tailing with high ash content (about 80%).
The I-Abβ locus was previously targeted to generate an I-Aβ-EGFP expressing mouse [10].
Differentially expressed hypothetical proteins, ROS-degrading proteins, and potential FFA transporters were targeted to generate 15 mutant strains.
EphB2 expression was determined by β-galactosidase staining in mice carrying an allele targeted to generate an EphB2 LacZ fusion protein [Henkemeyer et al., 1996].
Overall, the results demonstrate that the active site of this protein kinase can be targeted to generate an isoform selective inhibitor with in vivo CNS efficacy.
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Lockheed currently targets to generate 20% of its sales from international customers within the next two-three years.
In this study, we used gene targeting to generate transgenic P. berghei (Pb) parasites (designated as PfMSP1-19Pb) that express the MSP1-19 of P. falciparum (Pf) and the GFP reporter protein simultaneously.
(A ) Strategy for gene targeting to generate LPCAT3-deficient mice and for the identification of targeted clones.
To assess the function of PpHsp16.4 in stress tolerance, we used gene targeting to generate disruption mutants of PpHsp16.4 genes.
This was achieved by using gene targeting to generate a mouse that expresses Nf1 with a minor change that affects only the protein's interaction with Ras.
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