Exact(5)
Agadez is in north-central Niger, more than 600 miles from that attack site, but the militants have also targeted this region in recent years.
Four other miRNAs (miR-93, miR-125a, miR-302d, and miR-373) also targeted this region.
We targeted this region because, to our knowledge, it is the only section of the T. cruzi genome so far identified as being transcriptionally silent.
The binding of FoxO6 to this region in vivo was confirmed using CHIP assay, in which we found that FoxO6 specifically targeted this region without binding to the proximal promoter region.
The fusion constructs do not contain the 3′UTR of the endogenous gene, so we targeted this region using siRNAs to deplete solely endogenous HsSAS-6 without affecting the GFP fusion proteins.
Similar(55)
By targeting this region, a potent anti-IAV agent was subsequently created.
Such knowledge will be important in design of drugs to target this region.
However, it has been unsuccessful to generate anti-HIV neutralizing antibodies targeting this region.
Earlier research has shown that inhibiting the right DLPFC impairs cognitive control mechanisms, so Bachmann suggests that targeting this region could have increased the automaticity of the participants' responses, making them more likely to tell the truth.
A result of this is that consumer spending behavior differs immensely across the region and online retailers will need to take this into account when targeting this region.
Phage display with HIV-positive sera primarily results in the identification of immunodominant regions, such as KLIC, because of the abundance of antibodies targeting this region [41].
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