Sentence examples for targeted the expression from inspiring English sources

The LMNA G608G transgenic mice targeted the expression of the Hutchinson-Gilford progeria syndrome (HGPS) mutation in keratin-5-expressing tissue led to a typical phenotype of HGPS [16].

To investigate the role of EZH2 in the mammary gland, we targeted the expression of EZH2 to mammary epithelial cells using the mouse mammary tumor virus long terminal repeat.

To further demonstrate the role of VEGFR-2 as a target of these VEGFR-TKIs in the synergistic cytotoxicity observed in combination with lovastatin in MM cells, we specifically targeted the expression of VEGFR-2 employing short inhibitory RNA sequences (siRNAs).

Functionally, miR-133a can suppress tumor cell invasion and migration and targeted the expression of FSCN1.

We have targeted the expression of the light chain of tetanus toxin to the GF, to block chemical transmission, in shak-B flies.

To study the role that nuclear position and structure might have in ALS, we targeted the expression of DVAP-WT and DVAP-V260I in neurons and muscles.

The chicken genome has miRNAs that can potentially target the expression of the genes expressed from the segment 2 of H5N1 virus.

Additionally, immunofluorescence targeting the expression of CD11b, which is a molecular indicator of microglial activation.

Additional approaches are geared towards targeting the expression or stability of the BCR ABL kinase itself or targeting signaling pathways that are chronically activated and required for transformation.

However, viral miRNAs actively target the expression of cellular genes involved in relevant functions such as cell proliferation, DNA repair or RNA regulation.

As in other vertebrates, kisspeptins have been found to play a key role in the signal transduction, which targets the expression of gonadotropin-releasing hormone (GnRH) in the hypothalamus in fish (Tena-Sempere et al. 2012).