Sentence examples for targeted reactions from inspiring English sources

However, background compounds in water such as natural organic matter (NOM) can significantly hinder targeted reactions and removal efficiency.

(1 12): in-silico knock-out conditions are performed by setting parameter values (k i ) to 0 for targeted reactions in TRADD KO (1), cIAP1/2 KO (2), TRAF2 KO (3), TRAF5 KO (4) TRAF2/5 DKO (3,4), RIP KO (5), TRAF6 KO (6), TAK1 complex KO (7), LUBAC KO (8), SHARPIN KO (9), IκBα KO (10), MKK3/6 KO (11) and p38 KO (12).

Given the inhibition targets of each drug, we assume that a drug inhibits completely the enzymes responsible for the targeted reactions, hence stopping the relative fluxes.

Recognition and binding to specific lipids play a central role in targeting reactions, but it remains difficult to analyze the molecular features of such protein-lipid interactions.

Chromatinization of the target DNA inhibits both types of targeting reactions, presumably by impeding RNP access.

Thus far, however, efficient group II intron-based gene targeting reactions have not been demonstrated in eukaryotes.

Our results demonstrate the potential for using group II introns for gene targeting reactions in higher organisms.

Collectively, these findings suggest that the availability of host enzymes to complete group II intron gene targeting reactions will not be a limitation in most systems.

These findings indicate that chromatin poses a significant barrier to group II intron gene targeting reactions, presumably because it impedes access of group II intron RNPs to their DNA target sites.

To assay group II intron targeting reactions in X. laevis oocyte nuclei, we used a plasmid assay patterned after one developed to assay group II intron mobility in E. coli (Fig. 1A) [8], [8].

Here, by using group II intron RNP microinjection assays, we show that group II intron-based gene targeting reactions can occur efficiently in eukaryotes, but are dependent upon the injection of additional Mg2+.