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The most common example is 123I/131I for targeted radionuclide radiotherapy in differentiated thyroid cancer.
Conjugates of bisphosphonates with macrocyclic chelators open new possibilities in bone targeted radionuclide imaging and therapy.
The most common example of a theranostic is targeted radionuclide therapy.
Furthermore, the higher specific activity of 177Lu compared to commercially available 131I makes 177Lu preferable for targeted radionuclide therapies.
OP18 Development of radiohalogenated analogues of a avb6-specific peptide for high LET particle emitter targeted radionuclide therapy of cancer.
Among the cancer types which may benefit due to the treatment and diagnosis offered by targeted radionuclide delivery are medullary thyroid carcinomas (MTC).
For instance, the modality itself runs under various names such as "nuclear medicine therapy," "radiopharmaceutical therapy," and "(targeted) radionuclide therapy," in addition to "molecular radiotherapy," as used herein.
Since DOTA compounds are easy to label with β- or α-particle emitters like 177Lu, 213Bi or 225Ac, the tracers discussed in this paper seemed to be excellently suitable for bone targeted radionuclide therapy.
There was, however, no difference in the proportions of patients undergoing hepatic resection, trans-arterial chemo-embolisation, targeted radionuclide therapy, radio-frequency ablation or chemotherapy between the groups.
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Recently, FR-targeted radionuclide therapy was exemplified using a DOTA-folate conjugate which was labeled with 177Lu [177Lu
125 126 The main indication for mIBG imaging lies in selecting patients for high activity I-mIBG-targeted radionuclide therapy.
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