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Percentage of the entrance to target quadrant in the probe trial session was investigated.
Additionally, the time spent in the target quadrant on the probe trials was used as an indicator of targeted searching for the platform.
In the present study, quadrant Q3 was designated as the target quadrant.
The percentage of time spent in target quadrant by the animal was calculated.
D1R, 5-HT7R and 5-HT1AR were significantly correlating with the time spent in the target quadrant, representing retrieval in the MWM.
The rats in the LM groups spent more time in the target quadrant than the PC group (Fig. 8).
The probe trial revealed that diazepam-treated rats spent significantly less time swimming in the target quadrant.
As predicted, mice showed a significant higher exploration preference to the target quadrant; which was impaired by olfactory epithelium lesion (ZnSO4).
In MWM testing there were not significant differences in the training phase, the time spent in the thigmotaxia zone, or the target quadrant during the probe trial.
In the probe trial study, the time spent in the target quadrant was significantly shorter in PC group as compared to that in the NC group.
Furthermore, the shorter time in the target quadrant induced by scopolamine was significantly reduced by MEXX (100 mg/kg, p.o). (Fig. 4c, P < 0.05).
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CEO of Professional Science Editing for Scientists @ prosciediting.com