Though effective, prevention of TB in HIV positive by tuberculin skin testing and targeted preventive treatments is of limited clinical success [ 3, 4].
Additionally, when the systemic effects from specific microorganisms in oral biofilms are better understood, more targeted preventive treatment options may be recommended for persons at high risk for potential systemic diseases such as cardiovascular disease, and for aspiration pneumonia.
As we learn more about the precursors or prodromal manifestations of clinical psychopathology we will be able to examine the efficacy of earlier targeted preventive intervention approaches.
Of the 169 (theoretically) effective interventions included in the database of the Netherlands Youth Institute, 44 are preventive interventions (26.0 %), 72 are targeted preventive interventions (42.6 %) and 53 interventions are curative interventions (31.4 %).
These recent findings open new perspectives for identifying subgroups of patients at higher risk of developing invasive candidiasis and who may benefit from more specifically targeted preventive or preemptive antifungal strategies and/or of immunomodulating approaches [36].
The Air Force Surgeon General's office has asked the Johns Hopkins division to lead development of Patient-Centered PC2cision Cane, or PC2, an innovative program that will build on science and technological advances in genomics to ultimately deliver targeted preventive health care to Air Force personnel and their beneficiaries.
Because ovarian cancer is a leading cause of gynecologic cancer morbidity and mortality and DNA repair and response is a vitally-important pathway, the identification of genes and genetic variants in these pathways using a well-informed selection of SNPs may lead to the identification of genes for targeted preventive studies.
Second is the prospect of designing targeted preventive and therapeutic interventions (personalized medicine).
Accurate risk prediction would allow targeted preventive treatments, such as lifestyle or even pharmacological intervention.
This problem must be addressed through the development of adequate pediatric drug formulations, targeted preventive interventions, and treatment guidelines for young infants.
To develop targeted preventive strategies, it is necessary to determine the measures that can identify and predict spinal pain in children and adolescents.
