Sentence examples for targeted modifications from inspiring English sources

The Commission is expected to unveil in March "targeted" modifications to the rulebook that would tighten the external borders and improve Europe's asylum application rules.

Here we discuss the architecture of ZFNs and strategies for generating targeted modifications within the genome.

In particular, hybrid recombinases consisting of catalytic domains from the resolvase/invertase family of serine recombinases fused to Cys2 His2 zinc-finger or TAL effector DNA-binding domains are capable of introducing targeted modifications into mammalian cells.

To realize the full potential of plant synthetic biology, techniques are required that provide control over the genetic code – enabling targeted modifications to DNA sequences within living plant cells.

While ideally situations of low data availability would be addressed by increased sampling, this is not always possible due to economic, temporal or other constraints, and the shortage of high-quality species occurrence data requires the development of improved modelling frameworks, with targeted modifications to deal with specific problems (Lomba et al. 2010; Vicente et al. 2011).

We discuss the potential impact of these targeted modifications.

Over the past two decades, new technologies enabling targeted modification of plant genomes have been developed.

High rates of homologous recombination in Saccharomyces cerevisiae allow precisely targeted modification of specific yeast chromosomal genes, an attractive feature of this model organism.

"What are the moral implications of genome editing?" is the question that has been posed by the Nuffield Council on Bioethics regarding the new CRISPR-Cas9 mediated germ-line genome editing technique, which allows targeted modification of DNA sequences at the level of the germ-line, i.e. gametes (eggs and sperm).

A complete picture of the genes and molecular mechanisms underlying these traits is often lacking, which complicates targeted modification.

Recently, new technologies that use customized nucleases to facilitate targeted modification of genomic DNA have energized the field of genome engineering (Gaj et al. 2013).