Sentence examples for targeted modification from inspiring English sources

The CRISPR-Cas9 system works by making a precisely targeted modification in a cell's DNA.

We have recently demonstrated that triplex forming oligonucleotides can be used to mediate targeted modification of human disease-related genes.

Over the past two decades, new technologies enabling targeted modification of plant genomes have been developed.

Together, our findings establish N1MS as a nonototoxic aminoglycoside and support targeted modification as a promising approach to generating nonototoxic antibiotics.

High rates of homologous recombination in Saccharomyces cerevisiae allow precisely targeted modification of specific yeast chromosomal genes, an attractive feature of this model organism.

In a correctly targeted ES cell clone, the LOA assay detects one of the two native alleles (for genes not on the X or Y chromosome), the other allele being disrupted by the targeted modification.

Here we discuss the architecture of ZFNs and strategies for generating targeted modifications within the genome.

The Commission is expected to unveil in March "targeted" modifications to the rulebook that would tighten the external borders and improve Europe's asylum application rules.

Even certain targeted modifications may make sense.

CRISPR/Cas9, a gene editing technique, can make targeted modifications to DNA accurately, cost effectively and reliably.

We discuss the potential impact of these targeted modifications.