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CBM approaches to depression to date have targeted memory (Joormann, Hertel, LeMoult, & Gotlib, 2009; Raes, Williams, & Hermans, 2009), attention (Baert, De Raedt, Schacht, et al., 2010) and interpretation bias (Blackwell & Holmes, 2010).
Ken Paller, the paper's senior author and a professor of psychology at Northwestern, said: "We call this Targeted Memory Reactivation, because the sounds played during sleep could produce relatively better memory for information cued during sleep compared to information not cued during sleep.
The research, published in the journal Nature, specifically targeted memory cells in the hippocampus region of the brain previously identified by Tonegawa's team.
In a commentary accompanying the paper, two other psychologists, Gordon Feld and Jan Born, write: "The findings highlight the breadth of possible applications to permanently modify any unwanted behaviour by targeted memory reactivation during sleep".
The loci of these effects suggest that one factor driving differential cue processing is modulation of the degree of overlap between cue and targeted memory representations.
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The results point to the importance of conditioning to context specific sensitization and targeting memory re-consolidation of conditioning as a paradigm to modify sensitization.
They are targeting memory, because all these things mean nothing in their eyes," she told reporters.
Since the training procedure we have used involves an extensive acquisition phase, we also tested recent memory in a one-trial passive avoidance test to specifically targeting memory [24].
Specifically, our study was not designed to target memory processes, and we did not find a significant association between amyloid and memory performance.
Given the continuous increase in the prevalence of older people, a large number of interventions targeting memory loss are funded by public resources.
Detoxified, in-patient alcohol dependent patients received TAU plus two one-hour sessions of EMDR targeting memory representations of intense craving or relapse.
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