Sentence examples for targeted loss of from inspiring English sources

However, a functional role for p130Cas in non-motile cell types, including neurons, is likely equally important and recent studies in Drosophila showed that targeted loss of p130Cas in CNS neurons induced defects in neurite guidance and target fasciculation [ 100].

The overexploitation of fuel wood by rural communities in rural areas of the VBR, was partly responsible for the targeted loss of Woodland/Open bush to Thicket/Dense bush and Grasslands.

Schematic (top) indicates targeted loss of both Phox2b RTN neurons (purple) and RL Atoh1 neurons (orange).

Targeted loss of hub trees, however, can cross thresholds that destabilize ecosystems.

Schematic (top) indicates targeted loss of Phox2b RTN (purple) and Atoh1 RL (orange) neurons.

Schematic (upper right) indicates targeted loss of both Phox2b RTN (purple) and RL Atoh1 neurons (orange).

In contrast, no changes in gene expression are observed after the targeted loss-of-function mutation of AMPK in AgRP neurons [53].

We used RNAi to effectively produce animals with targeted loss-of-function in each of 28 individual, nuclear-encoded, structural subunits, and 2 assembly factors for mitochondrial complex I (Table 3).

Our method of targeted loss-of-function mutagenesis in combination with photo-cross-linking is designed to study the interaction of the antibody with residues that are substituted with photolabile UAAs.

Here, we describe a microplate-based detection strategy, with potential for high throughput, which is based on targeted loss-of-function mutagenesis and subsequent photo-cross-linking using genetically encoded UAAs to study antibody receptor complexes.

In summary, by using an IEC-targeted loss-of-function approach we show that expression of IEC PPAR γ is required for preventing colonic inflammatory lesions, up-regulating lysosomal pathway genes and increasing the production of the anti-inflammatory cytokine, IL-10, by CD4+ T cells in the MLN of mice with experimental IBD.