Sentence examples for targeted limits from inspiring English sources

However, reports of "off target" effects, whereby the CAS9 endonuclease is able to cut sites other than those targeted, limits the appeal of this technology.

Metoprolol therapy was discontinued in two patients because asymptomatic bradycardia occurred and heart rate remained within the lower targeted limits after one and two metoprolol dosages, respectively.

Fibrosis not only creates a physical barrier, but also replaces the muscle fibres that can be targeted, limiting the efficacy of cell- and gene-based therapies.

These results show that sialophorin targeting limits in vivo the growth of primary breast tumours.

Also, the requirement that parameters be fitted to data from arrays hybridized to each candidate target limits its usefulness for broad-spectrum microbial detection arrays.

This information can help improve conservation outcomes by understanding where to target limited efforts in a catchment, and clarifying the likely limitations of some aspects of scheme design.

Target limited resources.

Identifying those likely to develop adverse outcomes is important in order to target limited healthcare resources in an efficient and effective manner.

Current and future trials of CPT-11 will be aimed at evaluating three-drug regimens containing CDDP and CPT-11 in multimodality therapies and targeting limited-stage disease.

Usually the droplet erosion from the target limits the coating rate and the productivity of the d.c.-arc process.

The outlet contaminant concentrations were constantly held below target limits, in spite of remarkable fluctuations of the inlet concentrations.