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Word Health Organisation (WHO) targeted leprosy as one of the diseases to be eliminated from the world as a public health problem by reducing the prevalence to less than 1 case per 10,000 population based on the use of multi-drug therapy (MDT).
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Of the 122 countries targeted for leprosy elimination, 119 had achieved this goal by the early 21st century.
China officially announced that it had reached the World Health Organization (WHO) target for leprosy elimination at a national level in 1998 [ 1, 2].
The data provided in this study suggest a promising use for IFN-alpha boosting as a new prophylactic alternative to be explored in human leprosy by targeting host innate cell response.
BCG efficacy appeared to be significantly higher in studies when BCG vaccination was targeting household contacts of leprosy patients compared with the ones conducted in the general population: 68% vs. 53% [ 5].
This complex is targeted by thalidomide (Fig. 3, compound 16), a clinically approved drug for the treatment of multiple myeloma, leprosy and inflammatory bowel disease (Crohn disease) (Ref. 113).
Here, we assess the impact of different intervention strategies aimed at leprosy eradication through targeting non-symptomatic and symptomatic individuals.
The World Health Organization said it had met its target of cutting leprosy by 90percentt around the world in the last decade.
One of the current questions is how effective are the strategies established for the target of eliminating Leprosy as a public health problem [ 14].
Spatial targeting has been applied to control various infectious diseases, including leprosy [ 43– 43].
At its best, the study suggests that high level of case finding targeting non-symptomatic and symptomatic individuals, together with high level of compliance by individuals on treatment, may have a substantial effect on controlling leprosy relapses and possible may assist on attaining leprosy eradication.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com