Sentence examples for targeted induction from inspiring English sources
By contrast, Nrf2 and Akt1 mice lacked CO induction of Hmox1 and mitochondrial biogenesis, and CO rescued neither strain from S. aureus sepsis.We identify an inducible Nrf2/HO-1 regulatory cycle for mitochondrial biogenesis that is prosurvival and counter-inflammatory in sepsis, and describe targeted induction of mitochondrial biogenesis as a potential multiple organ failure therapy.
Xia, J. Y .et al. Targeted induction of ceramide degradation leads to improved systemic metabolism and reduced hepatic steatosis.
Targeted induction of certain GSV such as deletion, duplication and inversion is one of the most important tasks of genome editing for both analytic and therapeutic purposes.
Here, we show that kinetochores formed de novo by targeted induction of CENP-A assembly direct accurate segregation of the resulting HACs for many generations without any requirement for continued tethering of the exogenous HAT.
Thus, stem cell-like memory T (TSCM) cells are of key therapeutic value and efforts are underway to characterize TSCM cells and to identify means for their targeted induction.
Moreover, targeted induction of HO-1 has been shown to have therapeutic effects in various disease models.
To circumvent limitations of poor antigen presentation and immunogenicity of DNA vaccines that target induction of CD8+ T cell immunity, we have generated single chain MHC I trimers (MHC I SCTs) composed of a single polypeptide chain with a linear composition of antigenic peptide, β2-microglobulin, and heavy chain of a MHC class I molecule connected by flexible linkers.
The use of HRE promoter sequences to target induction of gene therapy approaches in the hypoxic microenvironment is a possibility, but has major issues for delivery.
Indeed, much of the current interest in developing new generation compounds is channeled towards designing LXRβ-specific ligands that target induction of the RCT pathway and circumvent the hepatic lipogenic signaling pathways mediated by LXRα.
Although Ali had already been declared ineligible for military service, the Army changed its eligibility standards, and suddenly Ali was targeted for induction.
To ascertain which of the Akap12 isoforms is targeted for induction with retinoids, exon-specific probes to each Akap12 isoform were designed and applied to samples of RNA from atRA-stimulated PAC1 SMC.
