Exact(26)
Novel adjuvant concepts include self-assembling particles and targeted immune delivery.
The combination of NPs with immune system-targeting moieties has paved the way for improved targeted immune therapies.
With different functional domains and optimized linkers, fusion proteins provide a solid base for targeted immune therapy for malignancies.
The scientific work that led to this breakthrough happened in the face of decades of widespread skepticism that targeted immune therapy for cancer would be possible.
Occasionally, kidney transplant recipients develop a state of targeted immune quiescence (operational tolerance) against an HLA-mismatched graft, allowing them to withdraw all immunosuppression and retain stable graft function while resuming immune responses to third-party antigens.
With some improvements in the expression system, it could be used to induce a targeted immune response against specific mucosal pathogens, and co-expression of several antigens would allow development of a novel multivalent vaccine.
Similar(34)
B) M ajor histocompatibility complex and interferon pathway genes important for cell-to-cell signaling, immune activation, and targeted immune-mediated cell death.
Moreover, current targeted therapies sometimes target immune system pathways.
To subvert immune surveillance, solid tumors disrupt tumor-targeted immune responses.
Lee, C. F. et al. Preventing allograft rejection by targeting immune metabolism.
Certain of these mechanisms target immune anti-tumor effector cells.
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