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Identifying pre-diagnosis factors that are predictive of dying within a short time interval following a cancer diagnosis should help us understand whether certain individuals (or groups of individuals) should be targeted for consideration of prompt PCP referral upon diagnosis.
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The question of relevant mutations was taken up and it was proposed that genes for chalones (C) and for chalone receptors (R) are logical targets for consideration in a two-mutation sequence.
At Boeing, this process has been targeted for elimination due to environmental and workplace safety considerations.
As protein kinases have been successfully targeted for inhibition in cancer, this diverse protein superfamily warrants consideration as a target for parasitic diseases as well [ 2, 5].
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