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For example, the degree of abnormality within the brain subdivisions varied depending on which RP gene was targeted (Figure 3B).
Of 372 G418-resistant ES cell clones, 4 clones were identified as being correctly targeted (Figure 1B).
In light of these results, we examined macroH2A1 localization in mouse embryonic stem cells (mESCs) in which both alleles of macroH2A1 are genetically targeted (Figure S1).
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The listed compensation includes targeted figures for long-term incentive compensation and is paid only to the extent that the company achieves its pre-established goals.
"The amount will be paid," Demant said in a statement, "with an upfront sum of $36 million with the remaining $14 million to be paid within a four-year period when sales and profits reach the targeted figures".
Mice lacking one allele of Tnnt2, designated Tnnt2+/−, were generated by gene targeting (Figure 1).
NPC cells expressing dominant negative ARF6, ARF6(T27N), exhibited no change in Ctx targeting (Figure S4).
We found no relationship between the population frequency of a 10-mer and CTL targeting (Figure 6).
None of these cell lines expressed high levels of WEE1 (Figure 4a), and, as expected, none was sensitive to WEE1 targeting (Figure 4b and 4c).
Differences between the electrostatics on the surface of the nematode proteins themselves and H. sapiens reflect opportunities for specific species targeting (Figures 4, S4, S5).
It did not provide a target figure.
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