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TTD provides therapeutic protein and nucleic acid targets and drug information including targeted disease and pathway [25, 26].
The essential elements include: (1) targeted disease syndromes, most often chronic lifestyle related syndromes, (2) organized approach to intervening, multi-disciplinary approach- physician, educator, and pharmacy.
Screening of plant extracts for their enzyme inhibitory effect is a quite popular pharmacological tool as it gives a preliminary idea about efficiency of a plant towards the targeted disease.
Such differences between regions may be useful for informing targeted disease control strategies.
Together they may be able to develop epidemiological genetic information that can lead to more effective public health interventions to treat the targeted disease.
The miRNA targeted disease genes category and their corresponding miRNA targets are listed in the online supplement (Additional file 1: Table S1).
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Few studies (16%) included targeted, disease-specific instruments.
Our results suggest that FP1201 could be the first effective, mechanistically targeted, disease-specific pharmacotherapy for patients with ARDS.
This rethinking will ultimately improve our ability to develop targeted disease-modifying therapy and to define subsets of the population that are likely to respond to these treatments.
Further understanding of the molecular mechanisms behind these effects should provide avenues towards targeted disease-modifying or -slowing treatments [ 5, 6].
In the early 2000s the international community responded to the Human Immunodeficiency Virus (HIV) pandemic, in addition to re-emerging Tuberculosis (TB) and on-going malaria epidemics, by creating targeted disease-specific funding mechanisms, termed Global Health Initiatives (GHIs).
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