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"targeted difference" is a correct and usable phrase in written English.
It is usually used when talking about specific or intentional discrepancies or disparities between things. Example: "The advertisement campaign was designed to highlight the targeted difference between our product and our competitors'."
Exact(3)
The DELTA project (Difference ELicitation in TriAls) conducted within the United Kingdom 2 examined how trialists determined the targeted difference in clinical trials.
The choice of 5% was conservative when compared with the targeted difference in protein intake in most large randomised trials that is 10% or more.
By estimating for the primary endpoint a standard deviation of 1.25 and a targeted difference in the mean scores between groups of 1, a type-I error of 5%, a power of 80% and a drop-out rate of 5%, the number of patients to be enrolled in each group was 26.
Similar(57)
Although this study did not include a control group, targeted differences between the pre-tests and post-tests should provide a first step towards evaluating the consequences of the embodied spatial training on spatial and mathematics outcomes.
Bigotry targeting difference can manifest just as easily based on sexuality as it can based on skin color.
It's been our position (QuERI's) that bullying is actually a regulating social process that targets "difference" and reaffirms what is considered "normal" or "acceptable" in a given school.
These targeting differences were robust to analyses using different background gene sets.
Here, we demonstrate how achieving specificity can be aided by targeting differences in the dynamics of proteins.
Hyung et al. reported that HA-decorated nanoparticles on the surface effectively targeted the CD44 receptor of CD44-overexpressed cells rather than lower CD44-expressed cells, while pure PLGA nanoparticles did not show targeting differences in both cells [7].
vi) Our study protocol did not target differences in the clinical presentation between UTI with and without prior UC use.
Because in vitro results are only influenced by the diffusion into the DC and the immunological binding characteristics of the antibodies, targeting differences between antibody preparations due to these factors can then be distinguished from differences due to pharmacokinetical properties.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com