Sentence examples for targeted cell cycle from inspiring English sources

In contrast, targeted cell cycle arrest halts BM movement and limits gap opening.

Matus, DQ, Chang, E, Makohon-Moore, SC, and Sherwood, DR. "Targeted cell cycle arrest halts basement membrane gap expansion during nematode uterine-vulval attachment". 2014.

A common challenge will be determining the proper combination, and sequence, of targeted cell cycle drugs and cytotoxic therapy.

In summary, the DNA content and immunoblot analyses indicate that the arrested NB4 cell populations show high enrichment for the targeted cell cycle phases.

Only patients showing the actively cycling, aggressive cell cycle phenotype are likely to benefit from conventional chemotherapeutic S-phase-directed or M-phase-directed agents or from the new generation of targeted cell cycle inhibitors that are now entering clinical trials.

This dose escalation study was designed to determine the recommended dose of the multi-targeted cell cycle inhibitor indisulam in combination with capecitabine in patients with solid tumours and to evaluate the pharmacokinetics of the combination.

Flow cytometer analysis was carried out to determine the effect of targeted and non-targeted micelles on the cell cycle progression of LNCaP cells (Fig. 7).

The clinical suspicion of FA is confirmed by the demonstration of increased spontaneous and induced chromosome breakage, excessive accumulation of cells in the G2 phase of the cell cycle, or targeted DNA sequencing.

However, in human glioblastoma cells, miR-195 targeted E2F3 directly leading to cell cycle arrest.

Analysis of cell cycle, changes in targeted signaling pathways and tumor characteristics were conducted to assess gefitinib and RAD001 interactions.

Although the gene expression profile characteristic for I-triggered DNA damage clearly suggest the ongoing cell cycle arrest in targeted cell cultures, it is unknown whether this halt in cell proliferation is reversible or not.